CYCLO (RGDYK)

Name	CYCLO(-ARG-GLY-ASP-D-TYR-LYS)
Synonyms	CYCLO (RGDYK) CYCLO(-RGDYK) cyclo (Arg-Gly-Asp-Tyr-Lys) CYCLO(-ARG-GLY-ASP-D-TYR-LYS) Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl)
CAS	217099-14-4

Molecular Formula	C27H41N9O8
Molar Mass	619.67
Storage Condition	-20 ℃, sealed, dry
In vitro study	Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for α V β 3 over α V β 5 (IC 50 =4000 nM) and α IIb β 3 (IC 50 =3000 nM).

biological activity	Cyclo(RGDyK) is a potent and selective inhibitor of αVβ3 integrin, the IC50 was 20 nM.
Target	IC50: 20 nM (αv β 3 Integrin), 3000 nM (αiib β 3 Integrin), 4000 nM (αvβ5 Integrin)

Last Update：2024-04-09 21:04:16

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CAS: 217099-14-4
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Product Name: Cyclo(RGDyK) Visit Supplier Webpage Request for quotation
CAS: 217099-14-4
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Product Name: CYCLO(-ARG-GLY-ASP-D-TYR-LYS) Visit Supplier Webpage Request for quotation
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